How To Treat Estrogen Dominance Through Diet And Lifestyle

Annex Naturopathic


How to treat estrogen dominance | Annex Naturopathic Clinic Toronto Naturopaths


Estrogen dominance is a sinister hormone imbalance that typically isn't caused by one single factor.


Our previous two articles - What Are The Causes of Estrogen Dominance?, and Estrogen Dominance: The Hormone Imbalance You're Told You Don't Have - outlined the main reasons why someone may have estrogen dominance and the health conditions associated with having poor estrogen metabolism.


Understanding that liver health, diet, inflammation and environmental exposures all play a crucial role in your estrogen health, here are a few simple changes you can make in order to optimize your estrogen status


1. Support liver health


We have a whole articleon why liver health is important, and now we know that liver health is also important in preventing estrogen dominance.


Improve your liver health by eating clean, emphasizing consumption of bitter leafy greens, drink a good amount of water and reduce your toxin load by reducing preservative-laden foods.


2. Eat Brassicae family (Cabbage) vegetables


This food group is particularly important in estrogen dominance.


Brassicae family vegetables contains a compound called Indole-3-carbinol (I3C), which has been found to favour healthy phase 1 conversion of estrogen to 2-OH-estrogens in women, which we know is protective against estrogen dominant conditions, while decreasing other metabolites (16-OH-estrogens), known to exacerbate estrogen dominant conditions (1-3).


This group of veggies are a great source of fibre, which is also great for binding and clearing estrogens, contain tonnes of antioxidants that help protect the liver against oxidative damage.


Members of this family include:



  • Broccoli

  • Cabbage

  • Cauliflower

  • Brussel sprouts

  • Kale

  • Rutabaga

  • Rapini

  • Kohlrabi

  • Bokchoy

  • Collard Greens


I always suggest lightly cooking these vegetables before consuming - raw forms can be hard on the stomach and can also slow down thyroid function.


3. Reduce stress


Practicing stress-relieving activities is good for overall health.


The stress hormone cortisol, when secreted in excess, will alter blood sugar metabolism - increasing glucose and insulin.


High insulin states perpetuate inflammation, and promote obesity, two risk factors for estrogen dominance.


Imbalanced cortisol on its own has been linked to higher inflammatory states. Progesterone, the hormone that balances estrogen and regulates its effects, is also lowered by high cortisol and inflammation.


Try reducing stress by exercising, practicing mediation and mindfulness.


You can read more about how to reduce stress from aprevious article.


How to treat hormonal imbalance | Annex Naturopathic Clinic Toronto Naturopaths


4. Eat clean meats and reduce meat consumption


Diet full of poor quality saturated fat and trans-fats promote inflammation - poor quality meats tend to be riddled with high amounts of these type fats.


Animals fed grain and corn aren't as lean and tend to be fed antibiotics and injected with hormones to increase their weight for greater profit.


These added chemicals not only increase the chemical load on our body when we consume these foods, the added hormones add estrogen to our bodies, promoting estrogen dominance!


Go with grass-fed, pasture-raised meats, or at least try to pick meats that are raised hormone and antibiotic-free.


Compounds found in well-cooked meat (heterocyclic amines and metabolites) can bind to and active estrogen receptors (4).To control levels of inflammation related to increased meat consumption, try eating 4-5 ounces, high quality red meat 1-2x a week, poultry up to 3x/week, and fish 2-3x/week.


Focus on legumes and eggs to fill the protein for the rest of your meals. If you go with soy, pick organic soy, and eat 1 cup cooked 1-2x/week for a balanced phytoestrogenic effect.


Dairy should be avoided as many people are sensitive to dairy and it's proteins (not just lactose), and milk from pregnant cows are very high in estrogen.


If you choose to eat dairy, go for ethically raised, organic cheeses and yogurt as they are better for the digestion, and stay away from liquid milk forms as a whole.


5. Avoid chemical products


As we saw, there are a number of chemical compounds that mimic estrogen in the body, increase aromatase, are liver toxic, and in general are carcinogenic.


Chemicals specifically found to lead to estrogen-dominant conditions, specifically cancers, include (4):



  • Found in cosmetic products and soaps:

    • metalloestrogens such as aluminum salts

    • parabens

    • cyclosiloxanes

    • triclosan (found in hand sanitizer)

    • phthalates

    • musk

    • UV sunscreens



  • Plastic packaging:

    • Styrene - a widely used plastic for food packaging

    • Bisphenol-A (BPA): the WORST - found to activate aromatase, lower progesterone effect, bind and activate estrogen




6. Balance your progesterone


Many women are walking around with low levels of progesterone, typically due to stress - which could be the biggest reason why estrogen dominance is present.


Symptoms of low progesterone include



  • PMS symptoms such as depression (intense), breast tenderness in the upper outer quadrants of the breast, acne, migraines and night sweats

  • Pre-menstrual spotting or spotting throughout the cycle (breakthrough bleeding)

  • Many women come in feeling that their PMS symptoms start long before 1 week before their menstrual flow - typically starting right after ovulation. This is a classic sign progesterone deficiency.


If you suspect that you might have estrogen dominance, progesterone deficiency, or you're unsure, book with one of us - we are able to provide a thorough assessment on your hormonal health.


We also offer testing to assess estrogen dominance through measuring the different estrogen metabolites (such as 2-OH, 4-OH, 16-OH) through urine testing.



If you're curious to learn more about this subject or would like to consult with one of our NDs feel free to book a visit or contact us.


Yours in Health,





Annex Naturopathic Clinic

572 Bloor St W #201, Toronto, ON M6G 1K1

-https://goo.gl/maps/uVRBvcyoUa62






References



  1. Rogan EG. The natural chemopreventive compound indole-3-carbinol: state of the science. In Vivo. 2006 Mar-Apr;20(2):221-8.

  2. Michnovicz JJ. Changes in levels of urinary estrogen metabolites after oral indole-3-carbinol treatment in humans. J Natl Cancer Inst. 1997 May 21;89(10):718-23.

  3. Reed GA., et. al. A phase I study of indole-3- carbinol in women: tolerability and effects. Cancer Epidemiol Biomarkers Prev. 2005 Aug;14(8):1953-60.

  4. Fucic A et. al. Environmental exposure to xenoestrogens and oestrogen related cancers: reproductive system, breast, lung, kidney, pancreas, and brain. Environ Health. 2012 Jun 28;11 Suppl 1:S8


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What Are The Causes of Estrogen Dominance?

The Causes of Estrogen Dominance | Annex Naturopathic Clinic Toronto Naturopath


Our last article outlinedwhat estrogen dominance is, and how liver health plays a role in estrogen metabolism and estrogen dominance.


There are a number of other causes for estrogen dominance - many of which are influenced by your day to day lifestyle.


It may be surprising to you to find out that many daily exposures can increase your chance of developing estrogen dominance.


Inflammation


Inflammation is the worst.


This chronic condition has been tied to basically all disease - heart disease, cancer, mental health conditions, to name a few. Inflammation plays a crucial role in the development of estrogen dominance.


As we know from the previous article, proper liver health is crucial for proper estrogen metabolism, and one way inflammation can impact estrogen dominance is burdening liver function.


However, there's another way inflammation can directly affect estrogen dominance - through activation of an enzyme called aromatase, a cytochrome P450 enzyme active in the liver, skin, bones, ovaries, adipose tissue, adrenal glands, brain and breasts - everywhere where estrogen has an effect on the tissue.


Aromatase is an enzyme that is key for estrogen synthesis in a healthy biological female and works in regulation with the body to keep estrogen conversion from androgens healthy and limited.


Estrogen dominant conditions, such as endometriosis, breast cancer, ovarian cancer, are associated with increased and dysregulated aromatase activity(1). There has been direct relationship between inflammation and aromatase activity, with much of the research looking in to how obesity, a disease of chronic inflammation, activates aromatase.


The link between inflammation and increased aromatase is a vicious cycle - increased adipose tissue is riddled with inflammatory structures (crown-like structures) which secrete pro-inflammatory signals.


These inflammatory signals increase aromatase activity in the adipose tissues, which in turn increases estrogen production. Excessive estrogen can cause problems with blood sugar (insulin resistance) and can mess with your hormone leptin, the hormone that makes you feel full - therefore promotes obesity.


These inflammatory crown-like-structures were not only found in adipose tissue but in breast tissue in overweight-obese women undergoing surgery for breast cancer.(2).


But it's not just related to weight - both obese and non-obese women with marked inflammation (detected on bloodwork), and conditions of inflammation such as insulin resistance (high blood sugar) are at higher risk of developing breast cancer through increased aromatase activity (3,4).


Pain occurs typically in response to inflammation, so it makes sense that if estrogen dominance is an inflammatory condition, why symptoms are centred around pain (painful periods, painful breasts).


Endocrine Disrupting Chemicals


There are a number of environmental causes for increases of aromatase activity. Bisphenol A (BPA) is a chemical commonly found in plastic that has been found to increase both aromatase and inflammation.


BPA has been deemed an ovarian, uterine and reproductive toxicant - therefore do not consume! (5) Other causes such as alcohol, chemical home care products, the birth control pill, smoking and pesticides (glyphosates) all increase aromatase activity (1).

BPA has also been found to increase the production of the bad estrogen metabolite, 4-OH-estrogen, compared to 2-OH pathway, which we know increases risk of estogen-dominant conditions (remember the last article?)


Not only do these chemicals increase aromatase activity, they can directly bind to estrogen receptors, stronger than actual estrogen, causing excessive estrogen-like effects on the tissue.


These are called xenoestrogens, can play a large role in the development in estrogen-related cancers such as breast cancers, uterine and ovarian cancer (7).


Xenoestrogens are a group of chemicals found in environmental pollutants (pesticides), chemical products (BPA in plastic) cosmetic products [parabens, metalloestrogens (cadium, aluminum), phathlates, musk etc].


Estrogen Dominance Hormonal Imbalance | Annex Naturopathic Clinic Toronto Naturopath


Progesterone Imbalance


This hormone is an important factor in estrogen dominance.


Progesterone is responsible for balancing estrogen, so appropriate levels of progesterone are important for preventing estrogen-dominant conditions.


Just like estrogen, progesterone is affected by inflammation - an inflammatory molecule called prostaglandin-E2 (PGE-2), not only stimulates aromatase, but also blocks progesterone receptor expression, therefore reducing the progesterone effect.


Progesterone can also be reduced in the face of high stress - this is because progesterone and the stress hormone cortisol, are made from the same ingredient, pregnenolone. When you're stressed, your body needs to make more cortisol, so progesterone production suffers.


High cortisol also encourages inflammation, as we know further encourages estrogen dominance by increasing aromatase, and blocking progesterone.


So now that we know environmental factors, stress and inflammation can also contribute to estrogen dominance, the next article will centre around how we can improve estrogen, progesterone balance and reduce inflammation through diet and lifestyle methods.



If you're curious to learn more about this subject or would like to consult with one of our NDs feel free to book a visit or contact us.


Yours in Health,



Annex Naturopathic Clinic

572 Bloor St W #201, Toronto, ON M6G 1K1

-https://goo.gl/maps/uVRBvcyoUa62






References



  • Patel S. Disruption of aromatase homeostasis as the cause of a multiplicity of ailments: A comprehensive review.J Steroid Biochem Mol Biol. 2017 Apr;168:19-25.

  • Morris P et. al. Inflammation and increased aromatase expression occur in the breast tissue of obese women with breast cancer. Cancer Prev Res (Phila). 2011 Jul;4(7):1021-9.

  • Brown KA et. al. Menopause Is a Determinant of Breast Aromatase Expression and Its Associations With BMI, Inflammation, and Systemic Markers.J Clin Endocrinol Metab. 2017 May 1;102(5):1692-1701.

  • Iyengar NM., et. al. Metabolic Obesity, Adipose Inflammation and Elevated Breast Aromatase in Women with Normal Body Mass Index.Cancer Prev Res (Phila). 2017 Apr;10(4):235-243

  • Peretz J et. al Bisphenol a and reproductive health: update of experimental and human evidence, 2007-2013.Environ Health Perspect. 2014 Aug;122(8):775-86

  • Kim EJ et. al Association between urinary levels of bisphenol-A and estrogen metabolism in Korean adults.Sci Total Environ. 2014 Feb 1;470-471:1401-7

  • Fucic A et. al. Environmental exposure to xenoestrogens and oestrogen related cancers: reproductive system, breast, lung, kidney, pancreas, and brain.Environ Health. 2012 Jun 28;11 Suppl 1:S8


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Estrogen Dominance: The Hormone Imbalance You're Told You Don't Have

Hormone Imbalance & Estrogen Dominance | Annex Naturopathic Clinic Toronto


As a female naturopathic doctor, I have a a great deal of experience in women's health issues. Much of it treating conditions likehormone imbalances andtheir effects on our quality of life.


Hormone imbalances are a complicated thing though.


Often times women will feel that their hormones are off, but after blood work and basic analysis, it's likely that everything will come back normal.


So how is it that hormones are normal, yet one day your body feels completely off, or that you one day find that you have fibroids? or endometriosis? or fertility issues?


What are some of the signs and symptoms that could lead you to potentially prevent and actually treat these conditions, instead of coming up with band-aid solutions to cover up the symptoms?


What is Estrogen Dominance?


Estrogen dominance is a hormonal condition that is often never detected in conventional medicine - the term dominance may indicate that a high level of estrogen would be detected on routine blood work, but this is not often the case.


In fact, estrogen typically comes back within normal range in women who have estrogen dominance - how is this so?


This is because estrogen dominance is a functional hormonal imbalance and is not a excess condition.


A functional hormonal imbalance indicates that while the body is clearly performing daily as it should, there are signs and symptoms that one experiences, whether it be mild or debilitating, indicate that the overall system is compromised.


This may not be a big deal, but if undetected and left untreated, can lead to chronic disease.


Signs and Symptoms of Estrogen Dominance


The interesting thing about estrogen dominance is that it's highly common in our society - many women experience symptoms of estrogen dominance monthly, some more severely than others.


The typical symptoms of estrogen dominance include:



  • PMS symptoms such as irritability, breast tenderness/swelling, premenstrual pain, acne, constipation, bloating, headaches

  • Painful periods

  • Irregular periods

  • Insomnia

  • Cyclical moodiness


Many women experience these symptoms and are told they are normal.


They are considered normal because these symptoms are a societal norm, meaning that many people have these symptoms so therefore it's normal, but from a health perspective, this is not normal!


If you have mild symptoms, it's likely that you're fine, but if any of these symptoms become severe and affect your day to day living, you definitely should consider being assessed for estrogen dominance.


Mainstream treatment for these symptoms usually involve being on hormonal contraception (birth control), anti-depressants, or pain-medications, and while these may help control your symptoms, none of these solutions actually target the root cause.


If the root cause isn't treated, it can lead to chronic disease


Hormone Imbalance & Hormone Tests | Annex Naturopathic Clinic Toronto


Associated Symptoms


When you have increased amounts of estrogen in your body, this can highly affect estrogen-sensitive tissues.


The tissues that are most affected are in the breast and uterus.


Why is breast tenderness and swelling caused by estrogen-dominance?


It's because your breast tissue is hyper-stimulated.


Why do you feel pain during your menstrual flow, or experience extremely heavy flows when you have estrogen-dominance?


This is because your uterine lining is hyper-stimulated by estrogen dominance.


When these tissues are hyper-stimulated, that leads to cell proliferation - long term cell-proliferation in the breast can lead to breast cancer.


Long-term cell proliferation in the uterus is called endometrial hyperplasia, which is a risk factor for uterine fibroids, endometriosis and uterine cancer.


What causes estrogen dominance?


Estrogen dominance is when there is an abundance of estrogen wrecking havoc on the body that isn't being balanced by other hormones, or properly cleared by the liver.


Reasons for why someone can have estrogen dominances are stemmed from:



  1. Biochemical imbalances and genetic-related dysfunction of liver detoxification

  2. Increased estrogen production due to chemical exposure and inflammation

  3. Relative excess due to another hormone deficiency

  4. Environmental and dietary exposure to xenoestrogens.


I will go through each of these reasons in detail inupcoming articles.


Today we will focus on liver detoxification.


Estrogen and liver detoxification


Estrogen is activated and then detoxified by the liver.


Liver detoxification occurs in phases.


Phase 1 Liver Detoxification


Phase 1 is responsible for exposing a hydroxyl-group (OH) to the estrogen (estrone E1 for this discussion) molecule, which breaks it down to many different estrogen metabolites with this OH group.


Each metabolite has it's own impact and function on the body. When the liver is working properly, it breaks estrogen down so the ratio of these metabolites favour optimal estrogen effect: an abundance of the protective 2-OH-E1 metabolite.


When the liver is having problems with phase 1, then it may favour the production of other estrogen metabolites, ones that have carcinogenic (cancer-causing) effects on the estrogen-sensitive tissue - these metabolites are 16-OH-E1 and 4-OH-E1.


The reason why the liver may favour the production of some metabolites versus the other comes down to which enzymes are activated. 2-OH-E1 is produce through the CYP1A1 enzyme, 4-OH-E1 through CYP1B1 and 16-OH-E1 CYP3A4, all of these are part of Phase 1 enzyme system called the Cytochrome P450 system.


One could have a genetic abnormality in the enzyme for 2-OH-E1 (CYP1A1), or could be lacking the essential cofactors to the enzyme, rendering the enzyme more sluggish and unable to keep up with 2-OH-E1 production.


One could also be exposed to environmental toxins that can also render the enzyme functionally slow, or simply have a diet that isn't rich in foods that favour the production of 2-OH-E1.


Or for some reason, the enzymes for 4 and 16-OH-E1 can be upregulated, favouring their production over 2-OH-E1.


Phase 2Liver Detoxification


Phase 2is all about conjugation - binding the now hydrolyzed estrogen to a methyl-group to exert further effects of the body and to prepare the estrogen for excretion out of the body.


2-OH-E1 and 4-OH-E1 are conjugated by the same enzyme called COMT - this enzyme is essential for turning these in to 2 and 4 -methoxy-E1. 2-methoxy-E1 is protective to the body, while 4-methoxy-E1 is neutralized by this process.


COMT is also important for producing antioxidants by the liver, which are protective against cancers. Therefore, if this enzyme is dysfunctional (for reasons as suggested for the other enzymes above), then the protective and neutralizing effects are diminished.


In fact, studies found that women who have genetic abnormalities in the COMT gene had higher risk for estrogen-related disease, such as uterine fibroids, endometriosis, breast and uterine cancer (see below for references).


This genetic susceptibility also has been found to be dependent on ethnicity - for example women of African descent being the one of the most susceptible groups for uterine fibroids.


What we do know is that liver health is important for regulation of estrogen-metabolism and can play a significant role on how we develop estrogen-related disease.


Our phase 1 and phase 2 health decline as we age, our exposure to environmental pollutants and our nutrition. Take a look at our article on Liver Health to find out ways we can improve the strength and functionality of our detoxification processes, potentially improving our estrogen health.


Next week we will go through how inflammation, and other hormone imbalances can be associated with estrogen dominance and nutritional and herbal strategies to improve our overall hormonal health and to prevent chronic disease.







If you're curious to learn more about this subject or would like to consult with one of our NDs feel free to book a visit or contact us.


Yours in Health,



Dr. Tanya Lee, N.D




Annex Naturopathic Clinic

572 Bloor St W #201, Toronto, ON M6G 1K1

-https://goo.gl/maps/uVRBvcyoUa62






References


1) Shen Y et. al. Role of single nucleotide polymorphisms in estrogen-metabolizing enzymes and susceptibility to uterine leiomyoma in Han Chinese: a case-control study.J Obstet Gynaecol Res. 2014 Apr;40(4):1077-84.


2)Huang CS et. al. Breast cancer risk associated with genotype polymor- phism of the estrogen-metabolizing genes CYP17, CYP1A1, and COMT: a multigenic study on cancer susceptibility. Cancer Res 1999. 59:48704875


3) Al-Hendy A, Salama SA., Catechol-O-methyltransferase polymorphism is associated with increased uterine leiomyoma risk in different ethnic groups.J Soc Gynecol Investig. 2006 Feb;13(2):136-44.


4) Zhao XM., et. al. Polymorphism of catechol-o-methyltransferase gene in relation to the risk of endometrial cancer. Zhonghua Fu Chan Ke Za Zhi.2007.42:116119


5)Juo SH, et. al., CYP17, CYP1A1 and COMT polymorphisms and the risk of adenomyosis and endometriosis in Taiwanese women. Hum Re-prod 2006. 21:14981502


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Botanical of the Month Red Clover (Trifolium Pratense)

Botanical of the Month - Red Clover | Annex-Naturopathic-Clinic-Toronto-Naturopathic-Doctor


As a Toronto naturopath, I like to educate my patients on how to incorporate local herbs and foods into their lifestyles for long term health.


Each month I'll be highlighting a local, seasonal, Ontario herb in order to help you understand and familiarize yourself with useful medical herbs and food that grow right outside your door.


You will be able to recognize these otherwise known weeds as powerful medicine that grow in harmony with your everyday surroundings.


We're seeing Red Clover (Trifolium pratense)everywhere!


My friend and I spotted these flowers earlier this July on one of our hikes and since then I've been seeing them on neighbour's lawns, parks, along the west Toronto railpath, even in one coming up through a sidewalk crack.


This is one of my favourite herbs to use in practice.


Red Clover is a perennial plant originating from Europe, Africa and West Asia, but has been naturalized all over the world.


It's characterized by its dark pink-purple flowering head, and trifoliate leaves, and grows to be about 20-80cm tall.


This plant is actually considered a legume/bean plant, being part of the Fabaceae/Papilionaceae family, which is home to many commonly known legumes such as peas, chickpeas, lentils and many beans.


Parts Used: Flowers heads


Uses for Red Clover


Edibility


Trifolium pratense flowers can be pulled off and eaten. The flower parts stimulate the salivary glands, making it great for chewing on when you're thirsty, or parched and don't have immediate access to water.


It can also be enjoyed as a sweet tea.


Medicine


Red clover exerts its actions best in females and children.


Detoxification and lymphatic drainage


Traditionally, red clover has been considered a blood purifier or alterative meaning that it cleans out and regulates the body.


This action refers to the specific ability of red clover to remove unwanted toxins (dead tissue, inflammatory molecules) from the blood through lymphatic stimulation, and breaks up thick blood through anti-coagulant actions.


Basically, it helps fluids to move efficiently throughout the body. This action makes Red Clover particularly useful in the treatment of chronic skin conditions, such as eczema, psoriasis and acne, particularly in children.


Red clover is also known to be used in coughs and bronchitis, particularly helpful in suppressing uncontrollable coughs, and in aiding the lungs to expectorate stubborn and accumulated mucus (Another pediatric application - is useful in children who catch the dreadfully persistent whooping cough).


It action on the glands of the neck and sinuses also help clear post-nasal drip (stubborn mucus dripping down the throat from the sinuses).


As mentioned above, red clover gently stimulates the salivary glands, making a great remedy for side effects of radiation or any condition where saliva production is compromised.


It's also great for single swollen lymph nodes


Women's health


Red clover is useful in the treatment in women's health conditions with either estrogen deficiency and estrogen excess.


Red clover contains chemical called phytoestrogens (isoflavinoids) that actually binds and activates the estrogen receptor. This make Trifolium pratense useful in mitigating menopausal symptoms, a life-stage for females characterized by declining estrogen.


Symptoms such as hot flashes, sleeplessness, weight gain, vaginal dryness and anxiety, can be directly linked to estrogen deficiency. However, the small amount of research studies on the effect of Red Clover on menopausal symptoms show mixed results in efficacy.


Maybe it's because the shape of phytoestrogens in red clover do not exactly fit the receptors in the vasomotor system (system responsible for many symptoms in menopause). What if it fit perfectly in the other systems of the body with all different types of estrogen receptors? There is almost zero research on this effect of red Clover, but it's a possibility.


Estrogen plays a protective role in many aspects of female health, so when females go through menopause, they are at higher risk for cardiovascular disease, and osteoporosis.


Not only can the phytoestrogenic effect potentially prevent these conditions, but the added antioxidant (flavinoids), and blood-thinning properties (coumarins and salicylates) also help.


Here's the controversy - if red clover contains phytoestrogens, wouldn't that increase your risk for estrogen-dependent cancers?


This is the question asked all the time when it comes to plants with phytoestrogen compounds, such as red clover and soy. The answer isn't simple, but if you want a simple answer, it's probably not.


Phytoestrogens do bind to estrogen-receptors, but they're actually considered protective against estrogen-dependent cancer, such as breast and uterine. This effective has been found in soy, another phytoestrogenic plant.


This is because phytoestrogens can competitively bind to estrogen receptor, blocking cancer-causing Xenoestrogens (found in plastics, pollution, chemical cleaners, hormone-laden meats) from binding and overstimulating the receptor.


When phytoestrogens bind to the estrogen receptors, the signal is less intense, more regulating (just like our own endogenous estrogens), and some phytoestrogens can actually block the signal, exerting an antagonistic estrogen effect.


There hasn't been enough research to confirm this clinically, however preliminary research studies has found taking red clover for a year does not seem to increase endometrial growth (leading to uterine cancer).


However, due to the lack of strong evidence, it's suggested that women with a history of estrogen-positive breast cancer, or uterine cancer, should avoid the use of Red Clover.


Field of Red Clover | Annex-Naturopathic-Clinic-Toronto-Naturopathic-Doctor


Forms


You can get red clover as a standardized capsule in powder form, basically taking it as a standardized pharmaceuticalmedication.


There are many products on the market that will sell Red Clover in this form for the use of mitigating menopausal symptoms.


Dueof the lack of consistent in the evidence on whether red clover helps menopausal symptoms, the abundance of other herbs that treat these symptoms really well, and the lack evidence on the safety of this herb in estrogen-positive cancers, I don't generally tend to rely on Red clover to treat these symptoms, especially at these higher doses. Though daily consumption of the tea can be used as a nutritive food for post-menopausal women who would benefit from the phytoestrogenic compoundsto prevent long term health problems associated with estrogen-deficiency.


I like using Red Clover as a tea or as a low-dose tincture. With the alterative regulating nature of the herb, and the consistent traditional use of Red Clover as a lymphatic stimulator, blood thinner and affinity to the neck and head glands , I generally tend to use Red Clover for regulating and detoxifying the body, specifically for the conditions mentioned earlier.


In children, teas and low dose tincture have a strong effect but tend to be gentle enough to prevent any unwanted effects.


Caution


Do not use Red clover if you have history of estrogen-positive breast cancer or uterine cancer, if you're on blood thinners, or have a clotting disorder.


If you're curious to learn more about this subject or would like to consult with one of our NDs feel free to book a visit or contact us.


Yours in Health,


Dr. Tanya Lee, N.D

Annex Naturopathic Clinic

572 Bloor St W #201, Toronto, ON M6G 1K1

-https://goo.gl/maps/uVRBvcyoUa62



References

1)Hoffman D. Medical Herbalism. Rochester, Vermont: Healing Arts Press, 2003.

2) Wood, M. Book of Herbal Wisdom, Berkeley: North Atlantic Books, 1997

3) Romm, A. Herbal Medicine for Women, London: Elsevier Health Sciences, 2017




To find more ways about health, wellness, and alternative medicine, please visit us here: naturopathic toronto

Does Gluten Deserve its Bad Reputation?

Is Gluten Bad? | Annex-Naturopathic-Clinic-Toronto-Naturopathic-Doctor-in-the-Annex-July03-01


At our naturopathic clinic in Toronto, in recent years especially, our naturopathic doctors are being asked about gluten more regularly.


"Is it good for me?"


"Is it bad for me?"


The infamous protein explained.


Gluten-free is definitely fashionable- but is it functional? Many people are opting to eliminate gluten from their diets- often with no diagnosis of celiac disease or gluten sensitivity.


Unfortunately, gluten-free is not synonymous with healthy.


Many gluten-free products are high in sugar, preservatives and unlike wheat flour, they are not fortified with vitamins and minerals.


Nonetheless, many people feel better when they take gluten out of their diet.


What is gluten?


Gluten is substance found in the endosperm of wheat, rye and barley grains. It is comprised of the proteins Gliadin and Glutenin.


Grains, and how we consume them, differs from that of our ancestral history.


Today grains make up a major part of our diet- remember the food group pyramid you learned in school- where the foundation was grains?


Well, that food pyramid is not something we share in common with our early human ancestors who ate almost no grains at all. The domestication of wheat happened about 10,000 years ago.


In more recent history, composition of wheat has changed due to hybridization of strains which has increased wheat's gluten content dramatically.


Gluten Sensitivity | Annex-Naturopathic-Clinic-Toronto-Naturopathic-Doctor-in-the-Annex-July03-01


What is it about gluten containing grains that irritates our gut?


Gluten can increase zonulin, a protein in the gastrointestinal tract that can cause leaky gut. Leaky gut, or intestinal permeability, occurs when the tight junctions (the connection) between intestinal cells open up, allowing larger molecules that shouldn't cross the intestinal barrier, to go into the blood stream causing inflammation.


It may not be the gluten alone, but the herbicides used in conventional farming are likely contributing to intestinal imbalances.


Glyphosate is a commonly used herbicide used in grain farming. If a substance can kills weeds and bugs- think about what it could do to the microflora in our gut (our healthy bacteria).


Glyphosate is known to kill beneficial bacteria and decrease the absorption of certain vitamins and minerals.


We do not definitively know the reason for the rising prevalence of gluten sensitivity.


It may be that a combination of increased wheat consumption, increased gluten content of wheat, and rising glyphosate residues in conventional grain products are contributing to dysbiosis, intestinal inflammation, and ultimately gluten intolerance.


What should you do?


Recommendations, in terms of complete gluten elimination, need to be made on an individual basis via comprehensive assessment by a qualified healthcare provider.


However, here are some recommendations that will benefit most individuals:



  • Reduce consumption of grains so that your diet favours protein and vegetables.

  • Eat organic and ancient varieties of wheat (einkorn or emmer) which would reduce pesticide residues and gluten content.


See a naturopathic doctor to assess if you have celiac disease or a gluten sensitivity in order to have a comprehensive plan that allows for optimal nutrition and overall health.


If you're curious to learn more about this subject or would like to consult with one of our NDs feel free to book a visit or contact us.


Yours in Health,


Dr. Marnie Luck, N.D

Annex Naturopathic Clinic

572 Bloor St W #201, Toronto, ON M6G 1K1

-https://goo.gl/maps/uVRBvcyoUa62





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Could You Be Gluten Sensitive Without Celiac Disease?

Gluten sensitive | Annex-Naturopathic-Clinic-Toronto-Naturopathic-Doctor-in-the-Annex


To eat, or not to eat wheat? That is the question.


The avoidance of gluten continues to be a hot topic in the media.


More and more people are opting for a gluten-free diet. For some people, eliminating gluten from their diet may be essential to not only maintaining the integrity of their gastrointestinal tract, but optimizing their overall health.


Digestion is the cornerstone of good health. If a person's digestive capacity is impaired, many other areas of a person's health can be adversely affected.


Not everyone who has a bad reaction to gluten has celiac disease. Non-celiac gluten sensitivity (NCGS) also negatively affects on the body, but does not produce the same disease process or complications that celiac disease does.


The naturopathic doctors at Annex Naturopathic Clinic are able to assess, diagnose and treat celiac disease and NCGS.


Dr. Luck and Dr. Lee can help determine whether or not you can include gluten in your diet and what treatment needs to be in place to heal the gut.


What is gluten?


Gluten is a protein found in wheat and some other grains including rye and barley.


What is celiac disease?


Celiac disease is an autoimmune condition.


Gluten causes the immune system to destroy intestinal cells. When intestinal cells are destroyed they lose their capacity to absorb nutrients causing chronic diarrhea, nutrient deficiencies and weight loss.


Celiac disease is associated with a much more serious risk profile than NCGS including neurologic dysfunction, osteoporosis, infertility, and other autoimmune diseases such as rheumatoid arthritis and Hashimoto's thyroiditis.


Why does celiac disease happen?


Genetics plays a strong role in whether or not someone will have celiac disease.


How is celiac disease diagnosed?


Serology (blood) testing for the antibodies against the intestinal tissues (endomysial antibodies (IgA EMA) and tissue transglutaminase antibodies (IgA tTG)).


If the antibodies are more than twice the normal limit, the patient likely has celiac disease.


Duodenal biopsy, tissue samples taken from the small intestine (which can only be ordered by a gastroenterologist), can confirm the serology testing.


These tests will only be accurate if the patient has ingested gluten consistently over the past 6 weeks.



What is non-celiac gluten sensitivity (NCGS)?


NCGS is a reaction to gluten that does not involve the immune system and does not cause intestinal cell destruction. Gastrointestinal symptoms include abdominal pain, bloating, constipation and diarrhea. NCGS can also contribute to joint and muscle pain, skin rash, anemia and depression.


Why does NCGS happen?


The working theory as to the increased prevalence of NCGS is a combination of increased wheat consumption and the hybridized gluten content of wheat- today's wheat contains far more gluten than it's ancient ancestor.


How is NCGS diagnosed?


NCGS is a diagnosis of exclusion.


When celiac disease has been ruled out, there are no signs of malabsorption and the individual has improves on a gluten-free diet, a diagnosis of NCGS can be assumed.


If you are experiencing adverse reactions to gluten it is important to have a thorough work-up.


If you're curious to learn more about this subject or would like to consult with one of our NDs feel free to book a visit or contact us.


Yours in Health,

Dr. Marnie Luck, N.D

Annex Naturopathic Clinic

572 Bloor St W #201, Toronto, ON M6G 1K1

-https://goo.gl/maps/uVRBvcyoUa62





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Best Home Remedies for Poison Ivy

For more natural health and wellness news, visit: goo.gl/zat81U-


By Dr. Mercola
Poison ivy, oak and sumac are closely related plants, and may be found growing in similar environments. In fact, all three grow throughout the U.S. except Hawaii, Alaska and parts of Nevada.1 Poison ivy is found throughout the U.S.; poison sumac is distributed mostly on the East Coast from Maine to Florida; and poison oak is found along the West Coast and the south from Texas to Florida and as far north as Illinois.2
While irritating and uncomfortable, poison ivy is not usually dangerous, unless the oil is aerosolized from burning. Inhaling the fumes can trigger an allergic reaction in your lungs. Nearly three quarters of the population of the U.S. will break out into a rash when exposed to the plant leaves. Only 25 percent appear to be resistant to the contact dermatitis...
[Read More ...]

Get your Vitamin D this Summer to Keep Colds and Flus Away in the Fall and Winter

Get Your Vitamin D | Annex-Naturopathic-Clinic-Toronto-Naturopathic-Doctor-in-the-Annex-June03-01


With summer finally here, you have the next 3 months to stock up on the important essential Sunshine vitamin, otherwise known as Vitamin D.


What Is Vitamin D?


Vitamin D is actually not a vitamin but is a hormone with beneficial effects on the immune system. It is widely known that we are able to synthesize Vitamin D on our own with the help of the wonderful summer sun, but in the dreary fall and winter months, achieving optimal levels of this miracle vitamin is difficult for us living in the Northern Hemisphere.


Vitamin D is commonly known to aid in the absorption of calcium, which leads to optimal bone health and function, but new research demonstrates that this hormone does much more.


Along with calcium regulation, Vitamin D is also a powerful immune and hormone modulator, which makes it useful in treating conditions such as hypertension, cancer, depression (especially seasonal), and prevention of the common cold and flu.


It has been demonstrated that those with low vitamin D levels have a greater risk of catching cold and flu bugs, and with limited amounts of sun exposure during the dark winter months, your levels of D will significantly drop.


Vitamin D helps your body fight off these infections by reinforcing the protective surface barriers of the skin, lungs, and the gastrointestinal tract, preventing unwanted microbes from entering the body through these routes.


This is especially important in those who are most susceptible to infection, such as people with weak lungs, (asthmatics, smokers, etc..) and those with general immune dysfunction, usually stemming from poor diet and lifestyle habits.


Vitamin D also modulates the immune system by activating T-cells, cells which help recognize and promote the destruction of microbes, while decreasing inflammation caused by an over-active immune system.


How Much Vitamin D Should You Take?


So what are adequate amounts of Vitamin D? According to Health Canada, recommended adequate intakes of Vitamin D is set at 200 IU daily (400 600 IU for those >50 years of age).


However, recent research has found that 200 IU/day (even up to 800 IU) is ineffective in achieving adequate levels of vitamin D in the bloodstream. Therefore higher dosages of vitamin D (at least 1000 IU) should be recommended by health care professionals to obtain adequate levels in the blood stream.


While sunlight is one of the best ways of achieving optimal vitamin D levels so stock up this summer as optimal levels are difficult to achieve in the winter months, or if you're stuck in the office all day.


All you need is 10 minutes in the mid-day sun in shorts in a T-shirt (without sunscreen) to get a mighty dose of vitamin D (10 000IU), but make sure to limit your time in the sun without sunblock to prevent skin damage.


For darker skinned individuals, it's more difficult to produce vitamin D through sun exposure alone, therefore vitamin D should be obtained through diet, longer sun exposure (but not too long to avoid skin damage, likely around 15-20 minutes maximum) and/or though supplementation.


Get Your Vitamin D | Annex-Naturopathic-Clinic-Toronto-Naturopathic-Doctor-in-the-Annex-June03-01


Other Sources Of Vitamin D


For the month with low sun exposure, there are various sources of vitamin D you can obtain through diet, such as though fish, eggs and fortified dairy and soy products.


However, it is recommended to also use high quality vitamin D supplement in conjunction with diet, as diet alone may not reach the optimal dosage and/or some of the fortified foods (dairy and soy) may not agree with your digestive system.


This summer, make sure to spend some much-needed time in the sun to optimize your vitamin D levels for the fall and winter season, when sunlight is sparse and darkness prevails. This will keep your immune system strong and protect your body from cold and flus.


Talk to a naturopathic doctor if you're curious about how to supplement vitamin D in the winter. Vitamin D testing is done in October in order to see what your status is going in to the low-light seasons, and a proper dose of vitamin D supplementation can be recommended based on your serum levels to maintain what you obtained in the summer


If you're curious to learn more about this subject or would like to consult with one of our NDs feel free to

book a visit or contact us.


Yours in Health


Dr. Tanya Lee, N.D

Annex Naturopathic Clinic

572 Bloor St W #201, Toronto, ON M6G 1K1

-https://goo.gl/maps/uVRBvcyoUa62





References:



  1. Health Canada [homepage on the Internet]: [updated 2006 June 29; cited 2010 Feb 2]. Available from: http://www.hc-sc.gc.ca/fn-an/nutrition/vitamin/vita-d-eng.php

  2. Rucker D, Allan JA, Fick GH, Hanley DA:Vitamin D insufficiency in a population of healthy western Canadians. CMAJ. 166(12): 15171524, 2002

  3. Heaney RP, Davies KM, Chen TC, Holick MF, Barger-Lux MJ: Human serum 25-hydroxycholecalciferol response to extended oral dosing with cholecalciferol. Am. J. Clin. Nutr. 77: 204-210, 2003

  4. Schwalfenberg GK. A review of the critical role of vitamin D in the functioning of the immune system and the clinical implications of vitamin D deficiency. Mol Nutr Food Res. 2010 Sep 7. [Epub ahead of print]

  5. Harris SSVitamin D and African Americans.J Nutr. 2006 Apr;136(4):1126-9.





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Crafty Uses for Carrot Seed Oil

Carrot seed oil is far removed from the ubiquitous orange vegetable and should not be mistaken for the cheaper macerated carrot oil. This humble essential oil is packed with natural healing properties, which have been used since the times of ancient Greeks and Indians. Learn more about carrot seed oil and how to get the most out of this plant oil.



What Is Carrot Seed Oil?



Carrot seed oil is derived from the dried seeds of the wild carrot plant (Daucus carota) of the Apiaceae or Umbelliferae family. Its plant source is an annual or biennial plant with hairy leaves and umbels of white lacy flowers and purple centers. Also popularly called wild Queen Anne's lace, its native origins can be traced back to Egypt, France and India.1 Carrot seed oil has a viscous consistency, a yellowish-brown color2 and a distinct woody, earthy and root-like fragrance.



Uses of Carrot Seed Oil



In traditional Chinese medicine, carrot seed oil has been proven to treat dysentery and to expel worms. But apart from these uses, it is also frequently:




Added into spicy foods and sauces in many Asian cuisines3


Mixed with other oils to infuse a woody note in Oriental and aldehydic perfumes


Used as a massage oil or bath oil to ease muscle pain


Used as a lotion to naturally and effectively tan and moisturize the skin





Composition of Carrot Seed Oil



The main chemical constituents of carrot seed oil include a-pinene, camphene, b-pinene, sabinene, myrcene, y-terpinene, limonene, b-bisabolene, geranyl acetate and carotol.4 It blends well with a wide range of essential oils, whether it's botanical, citrus or spicy oils. These include bergamot, juniper, lavender, lemon, lime, cedarwood and geranium oils.


The oil of the carrot seed primarily contains the well-known pigment carotene, but does not contain vitamins A and E or pro-vitamin A, which are found in the root.5



Benefits of Carrot Seed Oil



Carrot seed oil is perhaps one of the most underappreciated essential oils. But it is known to have antiseptic, carminative, cytophylactic, depurative, diuretic, emmenagogue and vermifuge (antiparasitic) properties.6 Here are just some of the other well-known health benefits of carrot seed oil:7

























Aids in healing abscesses, boils, and other skin disorders

Nourishes, tightens, and rejuvenates skin

Alleviates pain due to menstruation

Helps stimulate appetite

Helps treat ulcers

Improves liver and gall bladder disorder, particularly hepatitis, colitis and enteritis

Assists in stimulating the lymph system

Helps women in breast milk production after childbirth

Helps ease hiccups, colic and flatulence8

Relieves kidney stones and jaundice



Carrot seed oil is also widely used in vapor therapy or aromatherapy as a brilliant stress and anxiety buster and an efficient enhancer of respiratory and digestive functions. Read my article on aromatherapy and learn which essential oils work best for several health concerns you or someone you love could be suffering from.



How to Make Carrot Seed Oil



Carrot seed oil is extracted from the dried seeds through steam distillation, which is most commonly used due to its ability to excellently preserve valuable nutrients. The carrot seeds produce the most essential oil, but other parts of the plant can be used as well. In some cases, the dried seeds are crushed before going through steam distillation.


During this procedure, the botanical material is steamed to stimulate the release of its aromatic molecules. Careful temperature control is crucial - it should be hot enough to make the carrot seed essential oil come out from the plant material, but not too hot to the point of burning the material.



How Does Carrot Seed Oil Work?



To avail yourself of carrot seed oil's positive skin benefits, you can use it topically by applying a few drops of the essential oil on the affected area. Don't forget to mix your carrot seed oil with a with a carrier oil like coconut or olive oil for protection from its potential photosensitization and the other effects of its undiluted strength.


Others suggest diluting three to four drops of carrot seed oil in water and taking it orally at least three times a day to take advantage of its healing properties for respiratory and digestive issues. You should seek your doctor's advice before orally taking carrot seed oil or, in this case, any type of essential oil. This is to prevent undesirable health results.



Is Carrot Seed Oil Safe?



According to "Leung's Encyclopedia of Common Natural Ingredients," carrot seed oil is nontoxic. However, like other essential oils, never ingest carrot seed oil during pregnancy. Carrot seed oil can cause bleeding when taken by pregnant women. This caveat also applies to individuals with a history of epilepsy. If you or someone you know has epilepsy, do not use essential oils in general (especially in aromatherapy), as they can trigger overstimulation, which may lead to more serious adverse reactions.



Side Effects of Carrot Seed Oil



While carrot seed oil itself is said to have few side effects when used properly, its parent plant, the wild carrot, was found to increase risks of sun sensitivity due to its high furanocoumarin content, which has photosensitizing effects. It has also been reported to cause hypersensitivity reactions and occupational dermatitis.9


Do not apply carrot seed oil on your skin without mixing it with a carrier oil like coconut oil, olive oil, sunflower oil or hempseed oil. I also recommend staying indoors or covering parts of your body at least 72 hours after applying it on your skin. Ideally, you should perform a skin test first. Put a drop of carrot seed oil on a small portion of your skin and wait 24 hours. If any sign of skin irritation occurs, discontinue its use immediately.


Carrot seed oil overdose may cause vomiting and convulsions. I suggest you consult a natural holistic practitioner before incorporating carrot seed oil into your treatment protocol to avoid potential side effects.






Top 5 Ways To Improve Your Sleep Quality

Improve your sleep | Annex-Naturopathic-Clinic-Toronto-Naturopathic-Doctor-in-the-Annex


Are you getting enough sleep?


We've all felt the effects of poor sleep- fatigue, decreased cognitive function, craving for carbohydrate foods and caffeine, low motivation and mood.


Let's face it- everything's compromised when we are not sufficiently rested.


Most often, it's the small lifestyle changes that improve your sleep the most.


As naturopaths, the following are our top five recommended ways to help our patients increase the quality of theirsleep.


Top 5 Ways to Improve the Quality and Quantity of Your Sleep


1. Maintain a consistent wake-up and bedtime.


We can help establish a regular circadian rhythm by encouraging a healthy cortisol pattern. When our body is used to winding down at the same time each night our cortisol level drops appropriately. When we rise from bed at the same time each morning our cortisol level spikes to give us energy.


2. Eliminate the use of electronics (mainly anything with a screen) for 1-2 hours before falling asleep.


Many people spend their hours before bed doing work on their laptops, watching Netflix or catching up on social media on their smartphones. These activities can be very stimulating to the brain (and it's stress response). While at the same time, the blue lights coming from the screens themselves decrease the secretion of melatonin which is essential for restorative sleep.


Improve your sleep | Annex-Naturopathic-Clinic-Toronto-Naturopathic-Doctor-in-the-Annex


3. If possible, make your bedroom and electronic free zone.


About 8 hours of your day, or 1/3 of your life, is spent sleeping. The time you spend asleep (where there isn't any need for gadgets) is a great time to reduce exposure to electromagnetic fields- the frequencies/signals that are emitted by our electronics. Additionally, you won't have to lay beside a phone lighting up, buzzing or beeping with notifications.


4. Buy an old school alarm clock.


To respond a common rebuttal for the last point - but my phone is my alarm clock - you can buy a good old simple alarm clock to wake you at a consistent time everyday. Furthermore, if you wake up to check the time- you're not checking it on your phone where you may be tempted to check your notifications.


5. Write out what's on your mind.


Going to bed anxious and cycling through lists of things to do and open loops in your mind can undoubtedly reduce sleep quality and quantity. Getting what's in your head out on paper allows you to rest assured that you won't forget anything and you can look at it the next day when it is a more appropriate time to take action.


Although these recommendations are simple, creating new habits requires time and perseverance. The rewards of these habits, waking up refreshed and having improved health, are worth the effort!



If you're curious to learn more about this subject or would like to consult with one of our NDs feel free tobook a visit or contact us.


Yours in Health


Dr. Marnie Luck, N.D

Annex Naturopathic Clinic

572 Bloor St W #201, Toronto, ON M6G 1K1

-https://goo.gl/maps/uVRBvcyoUa62






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The Negative Effects of High Cortisol Levels

Annex-Naturopathic-Clinic-Toronto-Naturopathic-Doctor-in-the-Annex-June01-01


Cortisol is a commonly known hormone produced in the adrenal gland that sits on top of the kidney. Cortisol follows a daily pattern in which it rises rather rapidly in the first 10-30 minute after waking, increasing energy, then gradually decreases throughout the day so that it is low at night for sleep.


The cycle restarts the following morning.


In addition to being a factor in establishing diurnal rhythm, the production of cortisol is increased when the fight or flight response is triggered. This response is triggered in stressful situations.


What does cortisol do?


Cortisol effects metabolism by increasing blood sugar from the body's stores. It also influences the immune system by preventing the release of substances in the body that cause inflammation.


When individuals are under chronic stress, cortisol can become persistently elevated and lead to symptoms including:


Anxiety, depression, irritability.



  • Elevated cortisol influences enzymes and receptors for neurotransmitters which have effects on mood and emotion.


Carbohydrate, fat and/or salt cravings.



  • Cortisol is one of the hormones that raises blood pressure, it modulates brain regions that stimulate hunger for sodium and energy rich food. High sugar and high fat foods quiet the stress response because they trigger a dopamine release as a way to self-soothe by making us feel temporarily better.


High blood sugar and insulin resistance.



  • Cortisol raises blood sugar by signalling the production of blood sugar by the liver while at the same time opposing the action of insulin. This means that although there is high blood sugar, the body isn't able to use it.


Weight gain, especially in the abdominal region.



  • Cortisol opposes the actions of leptin, the hormone that tells us we are full after eating. At the same time, excess in blood sugaris converted to fat.


High blood pressure.



  • Cortisol triggers increased ingestion and retention of salt.


Annex-Naturopathic-Clinic-Toronto-Naturopathic-Doctor-in-the-Annex-June01-02


Insomnia and sleep disturbances



  • Cortisol can become dysregulated, rising in the evening (10pm second wind and difficulty falling asleep) and failing to spike in the morning (struggle getting up in the morning).


Hormonal imbalances and infertility.



  • Cortisol can inhibit the production of ovarian estrogen and progesterone. It can also decrease the frequency of ovulation.


Irritable bowel syndrome



  • Cortisol can cause decreased intestinal blood flow and altered movement of the gastrointestinal tract which leads to changes in the gut microflora.


If you suffer from any of the above symptoms and have a moderate degree of stress in your life- your cortisol levels may be a contributing factor.


Along with thorough intake, the naturopathic doctors at Annex Naturopathic Clinic use a specialized diagnostic test called an adrenal hormone profile to objectively assess cortisol production and metabolism.


Furthermore, NDs can help restore balance through lifestyle recommendations, herbal medicine and targeted nutritional supplementation.


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